Job Summary: 

• Build and oversee the Medicinal Chemistry group within Technical R&D
• Set the vision and strategy for the group and ensure execution of agreed deliverables
• Coordinate drug discovery activities externally involving chemists and biochemists
• Ensure external providers deliver to agreed targets which are monitored and aligned against milestones
• Contribute to the company’s molecular design strategy and oversee the Structure Activity Relationship (SAR) approach
• Contribute to the team’s review of data acquisition and any concomitant changes to strategic direction
• Foster and maintain a high degree of innovative and cutting-edge thinking within the early development phases of pipeline products
• Operate as a senior leader in the department providing focus on the operations and planning of the Technical R&D department, and ensuring teams have the resources needed to deliver to plan
• Responsible for maintaining cGxP and health and safety knowledge applicable to the role
• Provide high-level project management leadership for projects relating to Medicinal Chemistry
• Supervise internal medicinal chemists and lab-based synthetic chemists
• Supervise external chemists at overseas CROs to expeditiously deliver high quality compounds for biological evaluation
• Understand SAR, responsible for the design and development of novel NCEs
• Collaborate with and contribute to multidisciplinary research project teams

Skills on Resume:

• Team Management (Soft Skills)
• Strategic Planning (Hard Skills)
• Drug Discovery Coordination (Hard Skills)
• SAR Oversight (Hard Skills)
• Data Review (Hard Skills)
• Innovation Leadership (Soft Skills)
• cGMP Compliance (Hard Skills)
• Project Management (Hard Skills)

Job Summary: 

• Work closely and collaboratively with both internal and external colleagues across different disciplines
• Regularly update stakeholders with progress, budget status and recommend decisions and/or necessary changes
• Keep up to date with scientific literature and maintain awareness of development in the sphere of Medicinal Chemistry
• Undertake ongoing professional development by attending relevant training and conferences
• Create matrix teams in which individuals feel valued and are committed and engaged
• Develop and mentor less experienced staff to improve overall drug development experience within the Technical R&D function.
• Push drug discovery and chemical services and help lead the portfolio.
• Head of target identification with responsibility for assessment and selection of therapeutic targets entering the client’s portfolio.
• Building and growing the pharmaceutical R&D business and shape the future of the client, regarding integrated drug discovery and proprietary technologies
• Drive the structure-activity relationship (SAR)
• Co-lead a drug discovery project team with a biology co-leader to drive every aspect of the project
• Responsible for the success of chemistry aspects of the drug discovery teams through individual contribution and by leading a chemistry team
• Work closely with computational and structural scientists 
• Summarize data in an organized and presentable fashion

Skills on Resume: 

• Collaboration (Soft Skills)
• Stakeholder Communication (Soft Skills)
• Scientific Research (Hard Skills)
• Professional Development (Soft Skills)
• Team Leadership (Soft Skills)
• Mentoring (Soft Skills)
• Portfolio Management (Hard Skills)
• SAR Analysis (Hard Skills)

Job Summary: 

• Lead Medicinal Chemistry efforts for BridgeBioX small molecule drug discovery programs
• Design and execute medicinal chemistry strategies in an outsourced environment. 
• Manage synthetic chemistry CROs to deliver high-quality data in a timely manner
• Interpret biological and ADME data and design novel compounds that possess increasingly druglike profiles
• Collaborate with academic researchers to leverage external knowledge
• Manage interactions with cross-functional team leaders to support compound progression
• Develop, implement, and deliver on team collaborations: including initial proposal development, planning timelines and resources, monitoring milestones and final deliverables
• Provide well-organized reports and presentations to project teams and senior management
• Ensure effective collaboration with the discovery team and across other functions and sites to enhance program delivery and efficiency.
• Encourage and foster innovative thinking in all areas of departmental activity, with a particular focus on Medicinal Chemistry
• Create and execute a strategy to establish, protect and expand intellectual property
• Drive medicinal chemistry efforts on multiple projects in neurodegenerative disease therapeutic areas and deliver high-quality small molecule development candidates
• Design and execute hit-to-lead/lead optimization strategies for compound progression on discovery programs
• Provide both scientific and managerial leadership to chemistry CRO’s to synthesize NCEs

Skills on Resume: 

• Medicinal Chemistry (Hard Skills)
• CRO Management (Hard Skills)
• Data Interpretation (Hard Skills)
• Project Management (Soft Skills)
• Collaboration (Soft Skills)
• Strategic Planning (Hard Skills)
• Communication (Soft Skills)
• Innovation (Soft Skills)