Published: August 7, 2024 - The Computational Scientist applies advanced in-house and commercial simulation tools to optimize formulation processes such as granulation, blending, and tableting while ensuring high-quality data delivery within defined timelines. This role involves developing and validating numerical modeling and simulation tools, conducting process sensitivity analysis, and summarizing findings in technical reports. The scientist also collaborates with stakeholders to evaluate and innovate modeling tools, extends the software for neutron diffraction data processing, and stays updated with computational technology advancements for improved program recommendations.


Tips for Computational Scientist Skills and Responsibilities on a Resume
1. Computational Scientist, Genomic Solutions Inc., Albany, NY
Job Summary:
- Collaborate with experimentalists and computational scientists across the company to develop robust data science approaches to target identification and validation
- Integrate multiple levels of biological information to inform genome-protein-disease networks in the context of drug discovery
- Develop supporting evidence for the functional relevance of targets in human diseases and recommend follow-up experiments
- Help prioritize and triage potential drug targets using computational expertise and domain knowledge
- Identify novel data sources, computational methods, and external collaborations that will grow capabilities in computational target validation
- Assist in the preparation of scientific presentations, manuscripts and reports
- Interpret and communicate analytical information in a clear, concise manner
- Desire to work and problem-solve in a highly collaborative team environment, where colleagues frequently depend on one another
- Be open and transparent, holding themselves to high standards of scientific rigor and honesty
- Creates and presents tutorials, hands-on workshops, and documentation to train the research community.
Skills on Resume:
- Collaboration With Scientists (Soft Skills)
- Biological Data Integration (Hard Skills)
- Evidence Development For Targets (Hard Skills)
- Target Prioritization (Hard Skills)
- Novel Data And Methods Identification (Hard Skills)
- Scientific Presentation Preparation (Soft Skills)
- Clear Analytical Communication (Soft Skills)
- Team Problem-Solving (Soft Skills)
2. Computational Scientist, Quantum Analytics LLC, Boulder, CO
Job Summary:
- Works closely with faculty to identify, develop, and implement useful computational methods and resources that support or advance their research.
- Independently and proactively proposes and executes practical solutions to research challenges.
- Implements machine learning algorithms and summarizes findings.
- Develops, maintains, and supports data analysis and machine learning pipelines that include data collection, data management, data transformation, data analysis and documentation.
- Serves as the RCC Visualization laboratory point person.
- Develops and maintains data visualization software and tools.
- Assists faculty using the Lab and with exploring and applying new scientific visualization strategies, algorithms, and tools to their research.
- Keeps abreast of emerging visualization solutions.
- Engages the community of researchers involved in computational image analysis across application areas (e.g., biology, physics, chemistry, medical physics).
- Develops, tests, and documents scientific software in support of research goals.
- Works with faculty and their research groups to enable them to fully utilize the University’s and national computational resources for their research.
Skills on Resume:
- Faculty Collaboration (Soft Skills)
- Proactive Problem Solving (Soft Skills)
- Machine Learning Implementation (Hard Skills)
- Data Analysis Pipeline Development (Hard Skills)
- Visualization Lab Support (Soft Skills)
- Data Visualization Tool Development (Hard Skills)
- Scientific Visualization Assistance (Soft Skills)
- Emerging Visualization Solutions Awareness (Hard Skills)
3. Computational Scientist, Bioinformatics Innovations, Raleigh, NC
Job Summary:
- Implement and develop methods for processing 3D datasets, including point clouds and meshes, for feature extraction and environment reconstruction
- Develop data processing pipeline for light fixture characterization device
- Develop design calculators to aid in light fixture deployment
- Work with the software team to ensure data is delivered in a compatible format
- Work with engineering and product teams to understand product structures
- Develop scalable computational methodologies to identify splice-isoforms and/or neo-antigens specific to a population of cells via bulk and single-cell transcriptomic sequencing integration.
- Identify complementary public data for integrative analysis with proprietary datasets to identify potential antigens for therapeutic intervention.
- Develop interactive cloud-based tools for ease of viewing and access for single-cell datasets, including splice junctions.
- Propose and analyze new data types (e.g., mass spectroscopy) to identify post-translational modifications and relate inferences to transcriptomic sequencing data.
- Work collaboratively with experimental (wet-lab) teams to prioritize and test identified bioinformatic hypotheses.
Skills on Resume:
- 3D Data Processing Methods (Hard Skills)
- Data Processing Pipeline Development (Hard Skills)
- Design Calculator Development (Hard Skills)
- Software Team Collaboration (Soft Skills)
- Product Structure Understanding (Soft Skills)
- Computational Methodologies for Transcriptomics (Hard Skills)
- Integrative Data Analysis (Hard Skills)
- Cloud-Based Tool Development (Hard Skills)
4. Computational Scientist, Molecular Dynamics Labs, Madison, WI
Job Summary:
- Analyze large-scale omics datasets, interpret and communicate analysis results to stakeholders
- Integrate diverse types of biological data to identify leads for trait improvement
- Work closely with other computational scientists and trait scientists to help interpret data and generate hypotheses on how candidate gene function impacts traits of interest
- Contribute to the design of strategies for validating the function of candidate genes
- Provide consultations on experimental design, analytical methods, computational tools, and data interpretation
- Reaching beyond standard functional genomics approaches, explore new machine learning-based approaches for lead identification
- Report research findings (oral and written) at internal, local and national meetings.
- Independently lead computational projects, and contribute to written grants and manuscripts.
- Impact clinical and scientific research projects by designing complex technical programs and applications tailored to define leukemic and immune co-evolutionary states (for example) that influence patient outcomes.
- Analyze, develop and assist others in the development of formalisms, algorithms and software for complex applications, especially regarding intercellular interactions in silico.
Skills on Resume:
- Large-Scale Omics Data Analysis (Hard Skills)
- Biological Data Integration (Hard Skills)
- Data Interpretation and Hypothesis Generation (Soft Skills)
- Candidate Gene Function Validation Strategies (Hard Skills)
- Experimental Design Consultation (Soft Skills)
- Machine Learning-Based Approaches Exploration (Hard Skills)
- Research Findings Reporting (Soft Skills)
- Computational Project Leadership (Soft Skills)
5. Computational Scientist, EcoTech Research Group, Eugene, OR
Job Summary:
- Develop/modify/create pipelines for interpreting data from single-cell (and/or bulk data) experiments from publicly available and locally developed tools.
- Develop and maintain software tools and infrastructure for resolving specific problems.
- Independently design computational experiments, analysis approach and results interpretation.
- Analyze high-dimensional data from high-throughput profiling technologies (bulk and single-cell) such as whole exome sequencing and a range of single-cell approaches (e.g. RNA/TCR/ATAC/CITE-seq).
- Remain up-to-date on immunogenomic tools.
- Take responsibility for ensuring data organization.
- Advise and assist users and other personnel in analyzing, defining and resolving computer problems.
- Assist in the development, testing and revision of programs.
- Assist in applying advanced statistical methods, simulation models, and skilled programming
- Prioritize and manage multiple projects in a timely and resource-effective manner.
Skills on Resume:
- Pipeline Development for Data Interpretation (Hard Skills)
- Software Tools and Infrastructure Maintenance (Hard Skills)
- Computational Experiment Design (Hard Skills)
- High-Dimensional Data Analysis (Hard Skills)
- Immunogenomic Tools Knowledge (Hard Skills)
- Data Organization Responsibility (Soft Skills)
- User Support and Problem Resolution (Soft Skills)
- Advanced Statistical Methods Application (Hard Skills)
6. Computational Scientist, Neural Networks Corp., Tucson, AZ
Job Summary:
- Develop and design chemical property estimation algorithms using Quantitative Structure-Activity Relationships (QSARs) to elucidate hazard and risk profiles
- Update and enhance knowledge management applications for CBRN purposes
- Review and curate datasets for incorporation into models and tools
- Apply data science practices in the calculation and evaluation of statistical measures
- Build and expand CBRN databases
- Create modeling and simulation tools and web applications
- Perform software development and integration within an agile development process
- Support software lifecycle activities to include requirements development, software design, development, testing, and documentation
- Participate in software design and code reviews to ensure the delivery of quality products and enhance skill sets
- Plan and conduct software tests
Skills on Resume:
- QSAR Algorithm Development (Hard Skills)
- Knowledge Management Application Enhancement (Hard Skills)
- Dataset Review and Curation (Hard Skills)
- Data Science Practices Application (Hard Skills)
- CBRN Database Expansion (Hard Skills)
- Modeling and Simulation Tool Creation (Hard Skills)
- Agile Software Development (Hard Skills)
- Software Testing and Documentation (Hard Skills)
7. Computational Scientist, Precision Biotech Ltd., Columbus, OH
Job Summary:
- Define and develop analysis pipelines for scRNAseq data for T cell therapeutics.
- Apply rigorous statistical methods to drive actionable insights from internal and external datasets.
- Build data visualization and exploration tools.
- Collaborate with a diverse team of experimentalists, computational scientists, and clinicians to address key therapeutic questions in a data-centric manner.
- Build machine learning models based on genomic, biological, and clinical features to predict T-cell treatment outcome
- Build machine learning models with scRNAseq data to classify the quality of engineered T cells
- Explore public databases to understand the patient population landscape
- Work with computational scientists, data scientists, engineers, software developers, and geoscientists across the globe to develop, deliver and apply computational tools, models, or software to support business
- Enhance novel proprietary computational models and tools to address evolving business needs
- Use domain knowledge and subject-specific models (Eg. physics-based) – to solve science, engineering, and commercial problems and provide business insights
Skills on Resume:
- RNA-Seq Data Analysis Pipeline Development (Hard Skills)
- Rigorous Statistical Methods Application (Hard Skills)
- Data Visualization Tool Building (Hard Skills)
- Team Collaboration (Soft Skills)
- Machine Learning Model Development for Treatment Outcome (Hard Skills)
- Machine Learning Model Development for T Cell Quality (Hard Skills)
- Public Database Exploration (Hard Skills)
- Computational Tool and Model Enhancement (Hard Skills)
8. Computational Scientist, DataGen Solutions, Lincoln, NE
Job Summary:
- Whole-genome sequencing, bulk and single-cell RNA sequencing, and bulk and single-cell TCR sequencing of tumor and/or blood samples
- Integrating diverse research and clinical datasets generated from patient samples using different platforms and techniques
- Studies of resistance to existing and emerging cancer therapies using patient-derived data
- Studies of tumor evolution and progression and how it relates to the tumor-immune microenvironment using longitudinal patient samples
- Studies of cancer immunotherapies to develop predictors of response
- Support and conduct research within a translational and clinical research environment that involves curating and storing multidisciplinary data.
- Develop an understanding of cancer biology and cancer immunology key mechanisms
- Design, build and execute studies using proprietary or commercial tools to provide insights including calibrating models to field data and providing field optimization recommendations
- Lead and contribute to manuscript preparation as well as internal and external project-team reports
- Actively participating in project team and group meetings
Skills on Resume:
- Whole-genome and RNA Sequencing (Hard Skills)
- Data Integration from Diverse Platforms (Hard Skills)
- Resistance Studies Using Patient-Derived Data (Hard Skills)
- Tumor Evolution and Progression Studies (Hard Skills)
- Cancer Immunotherapy Response Prediction (Hard Skills)
- Translational and Clinical Research Support (Hard Skills)
- Cancer Biology and Immunology Understanding (Hard Skills)
- Study Design and Execution (Hard Skills)
9. Computational Scientist, Quantum BioLabs, Richmond, VA
Job Summary:
- Formulate research questions, design experimental protocols, collect data, analyze it, and communicate specific recommendations for how to use the results to improve product
- Review the literature to distill the gold standard measures for complex latent variables including cognitive skills and personality traits
- Translate those gold-standard laboratory paradigms into engaging and rewarding games, surveys, and other activities
- Identify specific gameplay elements in off-the-shelf games that might be able to measure variables of interest to users, then run experiments to put them to the test
- Write production code to process gameplay telemetry and other user data using the scientific Python ecosystem (Numpy, Statsmodels, Pandas, etc.)
- Work with the founding team to develop the overall product strategy and roadmap
- Collaborate with outside experts, corporate customers, and users on how the product can best support assessment and personalized learning and development at scale
- Integrating data across formats and sources by robust synchronization with existing datasets and databases
- Under general direction, developing innovative analytical methods to enable collaborators to interpret and design follow-up research
- Develop analytical methodologies into software tools that will be widely distributed and shared with the scientific community accessing data sets
Skills on Resume:
- Research Question Formulation and Experimental Design (Hard Skills)
- Literature Review for Gold Standard Measures (Hard Skills)
- Translation of Paradigms into Games and Surveys (Hard Skills)
- Gameplay Element Identification and Testing (Hard Skills)
- Production Code Writing for Data Processing (Hard Skills)
- Product Strategy and Roadmap Development (Soft Skills)
- Collaboration with Experts and Users (Soft Skills)
- Data Integration and Synchronization (Hard Skills)
10. Computational Scientist, Stellar Computational Services, Ann Arbor, MI
Job Summary:
- Applying in-house and commercial simulation tools to formulation processes including granulation, blending, and tableting among others.
- Developing numerical modeling and simulation tools with rigorous validation of the models.
- Delivering high-quality data within defined timelines and aligned with current industry expectations.
- Completing process sensitivity analysis, for example, digital design of experiments and rapid root cause analysis and summarizing results in a technical report.
- Collaborating with internal and external stakeholders to evaluate state-of-the-art modeling tools and develop new solutions.
- Research available methods for time-of-flight diffraction experiments
- Extend the DIALS diffraction analysis software for the processing of single crystal diffraction data from the ISIS pulsed neutron source
- Make the resulting neutron diffraction analysis software available within the Mantid package
- Plan efforts in broad mathematical uncertainty quantification modeling and GPU code-optimization and the relevant library areas of considerable novelty and importance where precedents are lacking.
- Stay abreast of new computational or mathematical technology or library developments to be able to recommend changes in the emphasis of computational programs or new programs warranted by such developments.
- Provide timely and accurate advice to other computational physicists who consult with the successful candidate
Skills on Resume:
- Simulation Tool Application (Hard Skills)
- Numerical Modeling and Validation (Hard Skills)
- High-Quality Data Delivery (Hard Skills)
- Process Sensitivity Analysis (Hard Skills)
- Stakeholder Collaboration (Soft Skills)
- Time-of-Flight Diffraction Method Research (Hard Skills)
- Diffraction Analysis Software Extension (Hard Skills)
- Mathematical Uncertainty Quantification (Hard Skills)