CELL BIOLOGY SCIENTIST JOB DESCRIPTION

A Cell Biology Scientist designs and runs the assay systems that determine whether a molecule moves forward or stalls. Mammalian cell culture, SOP authorship, and Electronic Laboratory Notebook discipline form the operational core. In biopharma drug discovery and biologics development, experimental rigor at this level shapes CMC regulatory submissions and clinical manufacturing decisions downstream. The work demands both independent bench execution and cross-functional collaboration with analytical, formulation, and QA teams.

As the Cell Biology Scientist, you will design, execute, and validate cell-based and molecular assays that directly inform compound progression and biologics pipeline advancement within a biopharma research or manufacturing organization. You will collaborate closely with cross-functional scientific teams, manage SOP and ELN documentation standards, and contribute experimental data that supports regulatory milestones and external partner deliverables.

Career Impact: Scientists who build deep expertise in mammalian cell culture, assay validation, and GMP-adjacent documentation develop a profile that opens doors to senior scientist and principal scientist roles within biopharma drug discovery and biologics development.

Business Impact: Assay data produced in this role directly determines which small molecules and biologics advance through the pipeline, making experimental accuracy a gating factor on clinical and commercial outcomes.

Growth Opportunity: Exposure to both early-phase discovery screening and late-phase process characterization gives scientists in this role a rare breadth that accelerates progression toward lead scientist or technical lead positions.

• Design and execute cell-based assays including tissue culture, cell growth, mobility, and invasion assays to support target assessment and compound progression.
• Perform molecular assays spanning nucleic acid extraction, immunofluorescence, ELISA, and RT-qPCR in cultured mammalian cells.
• Lead or support internal and external screening activities, coordinating with CROs and cross-functional partners as needed.
• Author and maintain Standard Operating Procedures and Electronic Laboratory Notebook records to meet regulatory and quality standards.
• Develop and optimize early and late-stage cell culture processes including scale-up, characterization, and validation activities.
• Analyze, interpret, and present experimental data to internal stakeholders and external partners at key program milestones.
• Collaborate with purification, analytical, formulation, QA, and regulatory teams to support batch release and manufacturing investigations.
• Contribute to continuous improvement initiatives that advance assay performance and process efficiency across the biologics pipeline.

• Ph.D. in Cell Biology, Molecular Biology, Biochemistry, Pharmacology, or a closely related field, or equivalent research experience.
• 3 or more years of hands-on laboratory research experience in an academic or biopharma industry setting, with direct involvement in cell-based assay programs.
• Extensive experience in mammalian cell culture and nucleic acid or protein delivery by transfection, transduction, and electroporation.
• Strong expertise in assay design, optimization, validation, and SOP development for cell-based and molecular biology applications.
• Demonstrated ability to manage multiple concurrent projects with disciplined record-keeping, attention to detail, and consistent on-time milestone delivery.
• Experience authoring or reviewing technical reports, batch records, deviation reports, or CMC regulatory documents.
• Strong written and oral communication skills with demonstrated ability to contribute to multidisciplinary scientific teams.

• Experience working with or managing CROs, including external screening coordination and data review.
• Familiarity with GMP cell culture manufacturing operations or manufacturing support in a biopharmaceutical setting.
• Background in cellular pharmacology and drug discovery within oncology or immunology therapeutic areas.
• Exposure to cell culture process scale-up, bioreactor culture, or bioprocess automation in a pipeline context.

• Assay reproducibility rate, reflecting the proportion of validated assays meeting defined acceptance criteria.
• SOP completion and ELN compliance rate, measuring documentation accuracy across active experimental programs.
• Milestone data delivery rate, tracking on-time submission of experimental results to program teams and external partners.
• CRO coordination turnaround time, measuring how efficiently external screening activities are initiated and closed.
• Deviation and CAPA closure rate, reflecting responsiveness to manufacturing or process investigations in GMP-adjacent work.

• Base Salary Range: $95,000 to $135,000 depending on experience and location
• Bonus: Annual performance bonus, typically 8 to 12 percent of base
• Equity: Stock options or RSUs common in biopharma and startup settings
• Health Benefits: Medical, dental, and vision coverage for employee and dependents
• PTO: 15 to 20 days annually plus federal holidays
• Common Perks: Professional development funding, lab equipment stipends, conference attendance support

Figures are estimates based on general US market benchmarks and may be outdated. Adjust based on location, company size, and seniority level.

Candidates for this position are evaluated without regard to race, color, religion, sex, national origin, age, disability, genetic information, veteran status, sexual orientation, gender identity, or any other characteristic protected under applicable federal, state, or local law. To support an inclusive hiring process, reasonable accommodations are available to applicants with disabilities upon request. Employment in this role is contingent on successful completion of a background check. All applicants must be authorized to work in the United States.

The Cell Biology owns the design and execution of cell-based and molecular assays that directly advance the company's validation platform. Working independently and alongside colleagues, this scientist delivers high-quality experimental data to stakeholders at key program milestones.

Key Responsibilities

• Work on a range of projects that directly impact the progress of the companies validation platform.
• Design and conduct cell-based experiments independently and in collaboration with colleagues.
• Execute cellular assays including tissue culture, cell growth, mobility, and invasion assays.
• Perform molecular assays such as nucleic acid extraction, immunofluorescence, ELISA, and RT-qPCR.
• Prepare experimental method descriptions and validate results in electronic lab notebooks.
• Analyze, interpret, and present data to various stakeholders.
• Deliver high-quality data consistently for key milestones in a timely manner.

Required Qualifications

• Ph.D. in Cell Biology, Molecular Biology, Biochemistry, or a closely related field.
• 3+ years of laboratory research experience in an academic or industry setting.
• Extensive experience in mammalian cell culture and DNA/RNA delivery by transfection, transduction, and electroporation.
• Deep hands-on experience with complex experimental design, molecular biology techniques, and RNA biology in mammalian cells.
• Strong expertise in assay design, optimization, validation, and SOP development for cell-based and molecular biology assays.
• Excellent project management, organization, attention to detail, and record-keeping skills.
• Strong written and oral communication skills with demonstrated ability to work collaboratively on multidisciplinary teams.

Embedded within a diverse scientific team, the Cell Biology Scientist designs and executes cell-based assays supporting target assessment, hit characterization, and compound progression for small molecule discovery programs. Working closely with internal teams and external partners, this scientist fosters a collaborative culture that advances world-class drug discovery science.

Core Functions

• Design, implement, and execute cell-based assays to support target assessment, hit characterization, and compound progression for small molecule discovery programs.
• Lead internal and external cell-based screening activities.
• Prepare and present data to internal teams and external partners.
• Write Standard Operating Procedures and maintain a high-quality Electronic Laboratory Notebook.
• Foster a collaborative culture to conduct world-class science within diverse scientific teams.

Qualifications and Experience

• Ph.D. in cell biology, biochemistry, pharmacology, or a related discipline.
• 2+ years of relevant industry experience.
• Deep understanding of cellular pharmacology and drug discovery in oncology and/or immunology.
• Broad knowledge of cell culture, cell line generation, and cellular readouts including transcriptional reporter gene assays, FRET, HTRF, NanoBRET, Western blots, plate-based ELISAs, and AlphaLISA.
• Proficiency in data analysis tools including curve fitting, image analysis, and data tracking and visualization within an ELN.
• Experience working with and managing CROs.
• Adaptability and flexibility to work in a dynamic startup environment.

Reporting to cross-functional biologics leadership, the Cell Biology Scientist leads development and optimization of early and late phase bio-processes supporting Incyte's pipeline of monoclonal and bispecific antibodies, fusion proteins, and other large molecules. Partnering with purification, analytical, formulation, QA, and regulatory teams, this scientist enables the advancement of pipeline molecules from clinical development through commercial launch.

Primary Duties

• Execute early and late-stage cell culture process development, scale-up, characterization, and validation activities.
• Lead technology transfer and clinical manufacturing activities toward development and commercialization of pipeline molecules.
• Serve as person-in-plant during key manufacturing and development activities at contract manufacturing and research facilities.
• Author or review technical reports, deviation reports, SOPs, batch records, CMC sections of regulatory documents, and tech-transfer documents.
• Collaborate with cross-functional teams including purification, analytical, formulation, QA, and regulatory to support batch release and manufacturing investigations.
• Present development and commercialization updates to internal functions and external partners.
• Lead technology development and continuous improvement initiatives to streamline biologics development.

Skills and Qualifications

• Ph.D. or Master's degree in Chemical Engineering, Biochemical Engineering, Biochemistry, or Cell Biology.
• Ph.D. with 3-5 years or Master's with 5-8 years of experience in cell culture process development and manufacturing support in a biopharmaceutical industry.
• Experience with cell culture process development, technology development, troubleshooting, and authoring and review of batch records.
• Experience managing multiple simultaneous projects both independently and as part of a team.
• Experience with cell line development, scale-up, technology transfer, design of experiments, bioreactor culture, bioprocess automation, process characterization, validation, and process risk analysis preferred.
• Experience in GMP cell culture manufacturing operations or manufacturing support beneficial.
• Experience authoring and/or reviewing CMC sections for regulatory submissions preferred.

Sitting at the intersection of translational research and biomedical informatics, the Cell Biology Specialist supports Axle Informatics by culturing human and animal cell lines, producing cerebral organoids, and maintaining meticulous records that enable research discoveries across global healthcare organizations. Operating across lab operations and cross-institutional collaborations, this specialist ensures continuous supply of cell lines and organoids to internal lab members and external partners.

Duties

• Culture human and animal cell lines including stem cells, fibroblasts, neurons, neurospheres, and organoids.
• Perform routine feeding, expansion, cryopreservation, and recovery of cell lines and maintain frozen stocks.
• Make human cerebral organoids and manage their ongoing culture, care, and supply to lab members and collaborators including shipping arrangements.
• Maintain meticulous records of all cell lines, frozen stocks, organoids, and procedures.
• Prepare stem cell and organoid media and maintain adequate stocks of media, culture reagents, and appropriate stock rotation.
• Ensure cleaning and maintenance of cell culture incubators and appropriate disposal of culture and laboratory waste.
• Follow all laboratory safety procedures including correct use of personal protective equipment.

Experience and Qualifications

• Demonstrated significant depth and breadth of subject-level expertise in cell biology.
• Awareness of the latest developments in relevant specialty areas.
• Experience conducting research and disseminating results through written reports.
• Strong organizational ability to plan, prioritize, and deliver work to meet required deadlines.
• Excellent oral, interpersonal, and written communication skills.
• Self-motivated, self-supervising, and resilient in achieving team objectives and overcoming obstacles.

A key member of the regional sales team, the Cell Biology Sales Representative manages the full sales cycle for Eppendorf's life sciences products across an assigned territory. Collaborating across a professional dealer network and an existing customer base, this representative builds relationships and captures market intelligence that drives regional revenue growth.

Functions

• Manage and finalize the whole sales process with customers.
• Provide excellent customer support within the assigned region.
• Strengthen existing customer relationships and acquire new customers within the assigned region.
• Conclude sales negotiations successfully and maintain relationships with professional dealership partners including onsite tutorials.
• Acquire and process market and customer data within the CRM system.
• Analyze market structures and competition and identify market potential.
• Develop and maintain the sales network including customers, influencing leaders, and professional dealers.

Background and Experience

• Bachelor's degree or university degree, ideally in a Science field.
• 2-5 years of proven sales experience, ideally within the Life Sciences sector.
• Excellent negotiation skills and business acumen.
• Knowledge of the Life Sciences sector preferred.
• Proficiency in MS Office products and CRM systems.
• Excellent command of English suitable for negotiation.

Consistent delivery of GMP-compliant cell therapy products depends on the Cell Biology Team Lead, who oversees manufacturing operations including cell and tissue culture, document control, and deviation management for a team of approximately four Biotech Associates. Based within a regulated manufacturing environment, this lead drives team qualification, coordinates logistics, and maintains quality standards from cleanroom preparation through batch handover.

Leadership Responsibilities

• Perform and supervise cell and tissue culture activities.
• Plan and coordinate work schedules, logistics, maintenance, and cleaning activities to deliver projects on time.
• Ensure generation, review, and approval of manufacturing documents in accordance with GMP regulations.
• Initiate and follow up on deviations, CAPAs, and changes in coordination with the QA department.
• Assist QE qualification activities and manage materials for cleanroom operations.
• Develop and qualify team members and ensure appropriate handover of information between teams.

Professional Experience

• BSc or MSc in biochemistry or biotechnology with focus on cell biology and/or human cell culturing techniques.
• Strong and proven tissue or cell culture knowledge.
• Experience in a GMP environment.
• Prior leadership responsibilities in previous roles.
• Strong communication skills with a proactive, flexible, and problem-solving approach.
• Fluency in English and additional languages are a plus.