ASSOCIATE SCIENTIST JOB DESCRIPTION

An Associate Scientist executes laboratory experiments with enough independence to advance a program and enough rigor to satisfy GLP and GMP scrutiny. Short on that balance, preclinical timelines slip and data packages reach regulatory reviewers with gaps. The role spans bench work in areas such as cell-based assays, bioanalytical method development, and in vivo study support, sitting within R&D or process development teams that feed directly into drug candidate decisions. What makes it demanding is the expectation to maintain meticulous documentation under GDP standards while adapting protocols as study data evolve.

As the Associate Scientist, you will design, execute, and interpret laboratory experiments that generate the preclinical and analytical data sets on which drug development decisions are based. You will work within a cross-functional research or process development team, collaborating daily with senior scientists, study leads, and regulatory affairs colleagues to ensure that study plans, SOPs, and data records meet GLP or GMP requirements.

Career Impact: Building hands-on expertise in GLP-compliant assay development and preclinical study execution positions Associate Scientists to advance toward Research Scientist or Senior Scientist roles within three to five years.

Business Impact: The analytical data and study reports this role produces feed directly into IND filings, drug release decisions, and safety assessments that determine whether a candidate advances to clinical trials.

Growth Opportunity: Exposure to both in vitro and in vivo methodologies, from flow cytometry and immunoassay design to pharmacokinetic sample analysis, expands the technical portfolio that commands higher seniority in the biotech and pharma job market.

• Design and execute in vitro and in vivo experiments according to approved study plans and SOPs, recording all methods and results in laboratory notebooks.
• Develop and validate analytical methods for assigned assay types, including cell-based, immunoassay, and bioanalytical formats, to meet study objectives.
• Analyze experimental data, interpret results against study hypotheses, and prepare draft reports and presentations for internal review.
• Troubleshoot assay, instrument, and equipment failures, implement corrective actions, and document resolution steps to prevent recurrence.
• Maintain laboratory equipment, manage reagent and consumable inventory, and support environmental and safety compliance within the work area.
• Collaborate with cross-functional partners including process development, analytical, and manufacturing teams to transfer methods and align on testing timelines.
• Contribute to GLP or GMP documentation including protocols, study reports, deviation records, and qualification summaries.
• Support regulatory submission activities by preparing data summaries and contributing technical content under the review of senior scientists.

• Bachelor's degree in biology, biochemistry, chemistry, or a related life science field, or equivalent work experience.
• Two or more years of hands-on laboratory research experience in a pharmaceutical, biotech, or contract research environment, with demonstrated study execution skills.
• Working knowledge of GLP and GMP frameworks, including GDP documentation practices and SOP adherence in a regulated laboratory.
• Proficiency in cell culture techniques, including maintenance, passaging, and quality control of mammalian cell lines.
• Demonstrated ability to perform quantitative assays such as ELISA, qPCR, or flow cytometry and to conduct subsequent data analysis with accuracy.
• Strong scientific writing skills, with the ability to produce clear laboratory records, draft protocols, and contribute to technical reports.
• Organizational skills sufficient to manage multiple concurrent experiments, prioritize competing deadlines, and escalate issues appropriately.
• Effective verbal and written communication skills, with comfort presenting data at team meetings and responding to scientific questions.

• Master's degree in a biological or chemical science discipline, with research experience in drug discovery or process development.
• Experience with in vivo study support including dose administration, sample collection, or necropsy in a rodent pharmacology model.
• Familiarity with bioanalytical sample preparation from biofluids such as plasma, serum, urine, or cerebrospinal fluid for downstream quantitative analysis.
• Prior exposure to method qualification or validation activities, including preparation of associated documentation under GxP requirements.

• Assay reproducibility rate, measuring how consistently repeated experiments fall within predefined acceptance criteria.
• On-time study completion rate, reflecting adherence to planned experimental timelines across assigned projects.
• Documentation audit pass rate, tracking the proportion of laboratory records that clear internal GDP or GLP review without major findings.
• Deviation and out-of-specification event frequency, indicating how effectively recurring instrument or assay failures are identified and resolved.
• Protocol and report turnaround time, measuring days from study completion to submission of draft documentation to the reviewing scientist.
• Typical tools: data analysis software (commonly GraphPad Prism or equivalent); laboratory information management systems (commonly LIMS platforms).

• Base Salary Range: $55,000 to $80,000 per year, depending on degree level and experience.
• Bonus: Annual performance bonus of 5 to 10 percent of base salary.
• Equity: Stock options or RSUs common at biotech employers; not standard at CROs.
• Health Benefits: Medical, dental, and vision coverage; employer contribution varies by company size.
• PTO: 15 to 20 days per year, plus federal holidays and sick leave.
• Common Perks: Tuition assistance, conference attendance support, laboratory safety allowances, and employee wellness programs.

Figures are estimates based on general US market benchmarks and may be outdated. Adjust based on location, company size, and seniority level.

Reasonable accommodations are available to applicants and employees with disabilities throughout the hiring process and in the workplace upon request. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, disability, genetic information, veteran status, sexual orientation, gender identity, or any other characteristic protected under applicable federal, state, or local law. Employment in this role is contingent upon successful completion of a background check and verification of work authorization in the United States.

The Associate Scientist owns the development and scaleup of chemical processes in a kilo-lab setting, integrating specialist knowledge in synthetic chemistry to solve problems across R&D projects. Reporting to the Research Manager and collaborating with internal and external networks, the Associate Scientist advances innovations in fine chemicals and process research that support patent filings, scientific publications, and business group outcomes.

Key Responsibilities

• Maintain specialist knowledge in synthetic chemistry and process research and integrate, apply, and develop it to solve problems in projects and assignments; involve in scaleup of chemical process in a kilo-lab setting.
• Stay abreast of new developments in the area of expertise and advise on applicability in business group processes.
• Propose and evaluate new ideas and support the initiation of R&D proposals and projects to contribute to innovations and new concepts.
• Execute agreed research programs and experiments, evaluate results, and report findings; plan and organize research activities aligned with Research Manager.
• Participate in assigned R&D projects in which the specific area of expertise is applied.
• Support and contribute to registration and patent filing in the field of expertise.
• Establish and maintain an internal and external network in the area of expertise.
• Participate in publishing scientific publications and presentations, attend scientific conferences and customer events, and keep up to date with scientific literature.
• Comply with Safety Health Environmental and Quality (SHEQ) and other legal requirements.

Required Qualifications

• PhD in organic chemistry or related methodology research, chemical catalysis, and fine chemicals, or MSc with 3+ years of experience in contract research organization, pharma, or fine chemical industry.
• Extensive knowledge and hands-on experience of modern synthetic methodologies and techniques.
• Experience in process chemistry and scale-up is an advantage.
• Experience conducting organic chemistry reactions and chemical process research, preparing chemical intermediates and nutritional products, and delivering cost-effective, scalable processes.
• Experience with structural identification and analysis of reaction side products and impurities with assistance from analytical teams.
• Ability to apply modern analytical instruments to synthetic work and study and apply new chemical technologies.
• Good communication and interpersonal skills.
• Fluent in Mandarin and English; knowledge of German is an advantage.

Embedded within a cross-functional engineering and science team, the Associate Scientist conducts assay and instrument testing using preproduction instruments to ensure integration with a new molecular diagnostic platform. Working closely with engineers, technical leads, and cross-functional validation teams, the Associate Scientist enables system robustness by troubleshooting assay-cartridge-instrument issues and executing validation protocols that advance platform readiness.

Core Functions

• Operate diagnostic platforms to evaluate system robustness and troubleshoot issues within assay-cartridge-instrument systems.
• Document system failures, upload, format, and annotate data to assist with root-cause analysis.
• Collaborate with engineers and scientists to implement and test corrective actions.
• Attend daily start meetings and interact with technical teams to communicate test results and receive task direction.
• Assist team leaders to solve assay-cartridge-instrument compatibility issues and implement engineering revisions to improve system robustness.
• Collaborate with cross-functional teams to generate validation protocols, reports, and project documentation, execute validations, and write validation reports.
• Assist engineers with instrumentation and component revisions to optimize assay performance.
• Run instruments to test system robustness and support validation testing.
• Provide status updates to supervisor and cross-functional teams.

Qualifications & Experience

• Minimum 2-year technical degree; prefer 3+ years of experience in a technical environment.
• Sufficient combination of instrumentation and engineering experience to work with minimum supervision.
• Some knowledge of medical instrumentation, associated software, and scientific principles and concepts.
• Operate standard laboratory equipment including pipetting and preparation of test cartridges.
• Good organizational skills and ability to troubleshoot and implement corrective action.
• Ability to work within cross-functional teams.
• Appropriate computer skills including email, word processing, and graphing software.

Reporting to laboratory leadership, the Associate Scientist monitors, conducts, analyzes, and records experiments across analytical research programs with limited supervision. Partnering with internal work groups and contributing to regulatory documents, patents, and publications, the Associate Scientist strengthens the organization's scientific output and quality data systems across multiple disciplines.

Primary Duties

• Monitor, conduct, analyze, and record experiments; provide data interpretation with limited supervision.
• Transfer experimental methods from literature to the lab and make modifications as necessary.
• Develop and implement new protocols with moderate review.
• Engage coworkers in scientific discussions and communicate data and interpretation to work group.
• Effectively troubleshoot equipment and experimental difficulties.
• Contribute to internal and external reports, papers, presentations, regulatory documents, invention disclosures, and patents.
• Present and defend analytical data at appropriate forums.
• Participate in department-wide support efforts such as safety.
• May train staff in the use of analytical instrumentation and methods.
• Coordinate and organize resources needed to complete tasks.

Skills & Qualifications

• Bachelor's Degree in Chemistry, Biology, Biotechnology, or related field with 2 years of related laboratory experience.
• Basic knowledge and hands-on experience with analytical techniques such as HPLC, UPLC, DNA, and immunoassays.
• Working knowledge of analytical methodologies and analytical instrument qualification programs.
• Skilled in developing systems to ensure quality data and proficient with standard laboratory equipment techniques.
• Excellent computer and technical writing skills.
• Ability to work independently or as part of a project team.
• Availability to work all shifts, overtime, weekends, and holidays as per business needs.

Sitting at the intersection of stem cell biology and drug discovery research, the Associate Scientist differentiates pluripotent and embryonic stem cells, executes in vitro assays, and generates stable cell lines to support a leading Bay Area biotechnology company's pipeline. Operating across multidisciplinary scientific discovery settings, the Associate Scientist advances drug screen programs and contributes research plans and SOPs that translate laboratory findings into actionable development outcomes.

Duties

• Differentiate pluripotent or embryonic stem cells into motor neurons, dopamine neurons, and other cell types in tissue culture.
• Screen and test agents in cell culture models using transfection, transduction, and molecular and biochemical methods including immunocytochemistry and microscopy.
• Generate and maintain stable cell lines.
• Contribute and write detailed research project plans and methodological SOPs.
• Design, plan, and execute in vitro assays using molecular biology and biochemistry methods.
• Analyze data using relevant statistical methods and present results.

Experience & Qualifications

• BS/MS with 2–5 years of industry experience.
• Experience performing drug screens in support of drug development; expertise in mammalian cell culture.
• Experience with imaging techniques such as immunocytochemistry, light and fluorescence microscopy; live cell imaging is a plus.
• Basic understanding of genomic, high-throughput sequencing, and high-throughput drug screening methods.
• Good communication skills and ability to collaborate across multidisciplinary scientific discovery settings.

A key member of a bioanalytical research team, the Associate Scientist develops and applies qPCR, digital PCR, and immunoprecipitation methods across biofluids and cell media to support investigative bioanalysis studies. Collaborating with study leads and cross-functional partners, the Associate Scientist delivers accurate data analysis and draft documents that advance biotech and pharmaceutical program objectives.

Functions

• Develop analytical methods using qPCR, immunoprecipitation, digital PCR, and sequencing from different biofluids and cell media.
• Perform sample testing and investigative bioanalysis of studies.
• Extract DNA and RNA and design RT-qPCR primers and probes for target sequences.
• Execute experiments and perform data analysis.
• Create draft documents and presentations of results.

Education & Experience

• Master's Degree in biology, biochemistry, chemistry, or relevant field with 1+ years of relevant industry experience, or Bachelor's Degree with 3+ years of relevant industry experience.
• Hands-on knowledge of analytical methods such as qPCR, ELISA, and immunoprecipitation with subsequent data analysis.
• Experience with oligonucleotides and biofluids including urine, serum, plasma, and CSF; automation experience is a plus.
• Understanding of PK, PD, and DMPK concepts.
• Familiarity with Excel, Word, PowerPoint, and analytical software such as GraphPad Prism or similar.
• Ability to multi-task and work in a fast-paced environment with minimal supervision.
• Excellent interpersonal skills and team player attitude.

Advancing preclinical research and drug discovery in a client's Gene Therapy group, the Associate Scientist II, Biology produces, purifies, and characterizes recombinant AAV vectors to support in vivo efficacy and safety studies while leading optimization of in-house AAV production methods. Based within a multi-disciplinary team and reporting to a supervisor, the Associate Scientist II, Biology enables regulatory compliance and scientific progress by maintaining the AAV database and contributing to patent applications and peer-reviewed publications.

Accountabilities

• Execute experiments under minimal supervision and communicate results as part of multi-disciplinary teams; may design and conduct independent research experiments.
• Analyze experimental data using analytical software such as GraphPad Prism and Excel.
• Apply relevant scientific principles and techniques to research problems.
• Maintain detailed laboratory notebooks and broad knowledge of state-of-the-art principles and techniques.
• Present findings internally and externally and contribute to peer-reviewed publications subject to internal scientific and legal approval.
• Provide technical and scientific input to project teams or research leadership and contribute to patent applications.
• Use in-house established methods to produce rAAV vectors for in vivo efficacy and pharmacology studies and lead development and optimization of new AAV production methods.
• Perform characterization of produced rAAV vectors including titer, purity, and transduction activity, and maintain database of AAV and plasmid vectors.
• Comply with all safety requirements and contribute to general lab operations including equipment maintenance, supply inventory, and clean work area maintenance.

Technical Qualifications

• Bachelor's degree in a biological scientific discipline with 4+ years of experience, or Master's degree with 2+ years of relevant experience.
• In-depth knowledge of cell biology and molecular biology including mammalian cell culture, cryopreservation, DNA/RNA purification, molecular cloning, PCR, RT-PCR, and qPCR.
• Experience with DNA/RNA transfection, Western blotting, ELISA, HTRF, and reporter assays.
• Working knowledge of NGS sequencing.
• Knowledge of AAV methodology is a strong plus.
• Knowledge of bioinformatics and ddPCR is a plus.
• Proficiency with Microsoft Office and GraphPad Prism.
• Ability to work with LIMS and databases.
• Effective verbal and written communication skills and analytical problem-solving ability.
• Effective planning, organization, and time management skills with ability to support multiple projects in a fast-paced, matrixed environment.

As the Associate Scientist, this role designs and executes novel in vivo preclinical studies in murine systems to support the development of an LNP/mRNA-based CAR-M immunotherapy platform at Carisma Therapeutics, in collaboration with Moderna. The oncology research team relies on this work to translate mRNA-based gene therapies toward the clinic, with the Associate Scientist contributing multi-color flow cytometry, immunoassays, and preclinical cell and gene therapy characterization that directly advance the company's oncology pipeline.

Role Responsibilities

• Develop and execute novel in vivo models in murine systems to support cellular immunotherapy platform development.
• Evaluate pharmacokinetics and pharmacodynamics of novel cellular therapies alone or in combinatorial therapy.
• Design, execute, and analyze ex vivo and in vitro experiments including cytokine secretion assays, cytotoxicity assays, and immunophenotyping.
• Analyze data, interpret results, and maintain accurate laboratory notebook records.
• Prepare summaries of findings and present at internal meetings and conferences.
• Perform mouse necropsy including tissue collection and processing, mouse handling and injections, and aseptic cell culture techniques.
• Plan and acquire multi-color flow cytometry panels and independently analyze flow data; perform immunoassays including ICS, ELISA, and ELISpot.
• Perform preclinical characterization of cell and gene therapy products and analyze datasets to make statistical conclusions.
• Work independently on in vitro and in vivo experiments and train, supervise, and mentor junior scientists.

Professional Experience

• MS/BS degree in immunology, biology, pharmacology, or related discipline with 5+/10+ years of experience in academia or industry.
• Experience with in vivo cancer models including xenograft and syngeneic models and mouse injections via IP, IC, IM, IV, SQ, and oral gavage routes.
• Familiarity with IsoPlexis, ddPCR, and single-cell RNA sequencing platforms; bioluminescence imaging experience.
• Excellent computer skills including Microsoft Suite, flow cytometry analysis programs, and data analysis and graphing software.
• Excellent verbal and written communication skills with strong ability to present data.
• Self-motivated with ability to operate effectively in a fast-paced entrepreneurial environment and work independently and collaboratively.
• Ability to train, supervise, and mentor junior scientists.

Associate Scientist delivers routine in vivo experimental functions in rodents, including dose administration, sample collection, necropsy, and husbandry tasks, within a pharmaceutical drug discovery and development laboratory. The work directly supports DMPK, ADME, and bioanalysis programs by ensuring accurate data summaries, calibrated equipment, and safe laboratory operations in compliance with company SOPs.

Day-to-Day Responsibilities

• Perform routine in vivo experimental functions in rodents including in-life observations, dose administrations, sample collections, sample analysis, necropsy, and euthanasia procedures.
• Train on various techniques to become proficient in in vivo procedures.
• Perform husbandry tasks including observations, cage change outs, daily cleaning, and operating the cage washer.
• Assist with routine vivarium facility environmental monitoring and laboratory waste management duties.
• Escort service engineers to appropriate work areas and assist with troubleshooting instrumentation.
• Participate in supply inventory and help order specific supplies using the JDE system.
• Perform routine laboratory techniques, prepare standard solutions, and maintain and calibrate laboratory equipment.
• Maintain research notebooks, perform routine calculations, tabulate and record results, and prepare accurate data summaries.
• Follow company safety policies and practices and develop knowledge of pharmaceutical areas including DMPK, ADME, In Life, Metabolism, and Bioanalysis.

Background & Experience

• Bachelor's or Associate's degree in animal science, biology, or related discipline.
• 0–3 years of relevant experience or 6+ years related experience with equivalent education and training.
• Basic understanding of scientific discipline and knowledge of concepts, practices, and procedures within drug discovery and R&D laboratory settings.
• Ability to perform preliminary lab work with supervision, follow instructions, and adhere to non-GLP guidelines and SOPs.
• Computer skills including MS Word, Excel, Outlook, and PowerPoint.
• Good oral and written communication, interpersonal skills, and time management skills to manage multiple projects within deadlines.
• Ability to work in a team environment, stand or sit for extended periods, lift up to 50 lbs frequently, and work in variable temperature environments with exposure to animals, biohazards, and chemicals.

The Associate Scientist generates high-quality immunoassay data within the Ligand-Binding Immunoassay team, performing Luminex assays to support toxicology and clinical studies across Pfizer's vaccine programs in a regulated GLP setting. Reporting within the team and collaborating with cross-functional groups, the Associate Scientist shapes the accuracy of clinical and non-clinical testing by maintaining cGLP compliance, complete records, and reagent and equipment readiness across multiple programs.

Key Responsibilities

• Perform clinical assays in accordance with cGLP requirements and SOPs, including Luminex assays to support toxicology and clinical studies.
• Perform assays to support critical reagent testing and qualification, assay development, and troubleshooting.
• Perform various duties to support assay throughput including supply management, reagent preparation, data review, equipment maintenance, and inventory.
• Assist in maintaining the laboratory including ordering and restocking supplies and ensuring cleanliness and compliance.
• Document all aspects of assay throughput to maintain accurate and complete records according to current cGDP requirements.
• Assist in managing records and documents associated with ligand-binding immunoassays including data archiving, SOPs, and reports.
• Build basic team effectiveness skills including communication, collaboration, and consensus management within the immediate work group.
• Present experimental and project results at group meetings and provide progress updates when required.
• Complete all cGLP, safety, and site training in conformance with departmental requirements.

Qualifications & Experience

• Bachelor's or Master's degree in biology, microbiology, molecular biology, chemistry, or relevant field of science; non-PhD position.
• 0–3 years of experience in a relevant field; hands-on experience in a laboratory setting including pipetting.
• Basic knowledge of cGLP/GDP and experience working in a regulated laboratory environment.
• Basic knowledge of Luminex technology.
• Proficient in Microsoft Office including Excel, Word, and Outlook.
• Ability to work in a matrixed, collaborative environment and communicate effectively within and across teams.
• Ability to work independently, manage responsibilities, and prioritize work assignments; strong attention to detail and excellent record-keeping abilities.

Embedded within the Sizing & Morphology platform of Analytical R&D, the Associate Scientist plans and executes laboratory activities to characterize the structure and morphology of vaccines using microscopy-related techniques from early candidate stages through phase III validation. Working closely with Technical R&D departments including Drug Substance, Drug Product, Statisticians, and GIO/QC organizations, the Associate Scientist advances method development according to Quality by Design principles and ensures the integrity of analytical documentation and results.

Core Functions

• Plan and execute lab activities in collaboration with team members to characterize structure and morphology of vaccines using microscopy-related techniques.
• Participate in lab organization and maintenance including ordering reagents and consumables and following up on instrument maintenance and repair.
• Participate in analytical method development and implementation of innovative technologies according to Quality by Design principles.
• Interpret and report results after extensive raw data quality checks and participate in double-checking results from other team members.
• Generate appropriate analytical documentation including protocols and reports.
• Present results in internal meetings within the team and across analytical sub-teams.
• Interact with Technical R&D departments including Drug Substance, Drug Product, Statisticians, Preclinical, and GIO/QC organizations.
• Participate in scientific and technology watch in the domain of competency.

Skills & Qualifications

• Master's degree in Chemistry, Biochemistry, Biophysics, Biology, Bioengineering, Chemical Engineering, Pharmacy, or related discipline.
• Expertise in at least one of the following microscopy techniques: TEM including cryo-EM, SEM including EDS, CLSM, or AFM.
• Experience or awareness of light scattering techniques, NTA, SEC, FFF, AUC, or disc centrifugation is a plus.
• Knowledge of single-particle analysis, software, instrumentation, and image analysis is a plus.
• Knowledge of SAP tool for results recording, validation, deviation, and CAPA management.
• Sound scientific methodology and thinking with commitment to problem solving and innovative solutions.
• Communication skills in oral and written form with ability to engage the team; result- and quality-oriented.
• Native language of the team is French; English fluency is an asset.

Reporting to the Analytical R&D Microbiology organization at Pfizer's Andover facility, the Associate Scientist applies GMP microbiological methods including bioburden, LAL, and qPCR to assess product quality and support environmental monitoring of Drug Substance and Drug Product facilities. Serving as a contributor to a multi-disciplinary team, the Associate Scientist enables the compliant development of biological therapeutics by executing in-process, release, and stability testing and maintaining rigorous cGMP records.

Primary Duties

• Apply GMP microbiological methods including bioburden, LAL, PCR, and qPCR to assess product quality and detect impurities.
• Support GMP in-process, release, and stability testing of clinical supplies using established microbiological methodologies.
• Become proficient in aseptic lab technique and facility gowning for environmental monitoring, bioburden, LAL testing, microbial identifications, and qPCR.
• Record, archive, and report all data in compliance with cGMP guidelines.
• Interact effectively with peers and leaders as part of a multi-disciplinary team in a fast-paced environment.

Education & Experience

• BS in microbiology, biochemistry, biology, or related field.
• 0-3 years of experience in a biotech or pharmaceutical GMP laboratory setting.
• Experience with Quality Systems in a GMP environment and some knowledge of drug development processes for biological candidates.
• Excellent documentation skills and ability to follow established procedures under minimal supervision.
• Experience with laboratory data systems such as LIMS.
• Self-motivated and highly effective in a team-based environment with effective oral and written communication skills.

The Associate Scientist delivers laboratory experiments supporting the global cryogenics and cold chain process for commercial biologics drug substance, covering bulk fill, freeze-thaw operations, and shipping qualification studies. Reporting to the Cryogenics & Cold Chain Sciences team within MS&T and partnering with cryogenics, analytical, operations, and manufacturing teams, the Associate Scientist enables process characterization and improvement outcomes that protect drug substance integrity across the supply chain.

Scope of Work

• Conduct laboratory experiments to provide commercial support for cold chain biopharmaceutical manufacturing processes including bulk fill, handling, freezing, storage, and cold chain shipping operations for biologics drug substance.
• Operate and maintain laboratory equipment, manage lab supplies, prepare buffers and reagents, and execute development studies.
• Perform data analysis and interpretation, document experimental data and results in laboratory notebooks, verify data, and prepare final reports.
• Follow appropriate GLP/GMP procedures when applicable.
• Work effectively across multiple cross-functional areas and independently to accomplish project goals.

Requirements

• B.S. degree in Pharmaceutical Sciences, Biological or Chemical Sciences/Engineering, or related discipline.
• 6+ months of experience in a professional industry setting or multiple years in an academic laboratory setting, including preparation and handling of test solutions, experimental design, protocol execution, operation of analytical instrumentation, data analysis, and report authoring.
• Knowledge of common protein analytical tools including pH measurement, UV-vis spectrophotometry, and HPLC; knowledge of protein freezing/thawing, formulation, and stability is desired.
• Good verbal and written communication skills and excellent interpersonal skills with ability to work in a team environment.
• Good organizational skills, strong attention to detail, excellent troubleshooting aptitude, and self-motivated work style.

Sitting at the intersection of sample management and bioanalytical science, the Associate Scientist, Sample Preparation prepares biological samples for method validation and supports method development and troubleshooting in a GLP environment. Operating across interactions with LCMS Analysts, Study Leads, and the Sample Management team, the Associate Scientist, Sample Preparation ensures accurate, compliant sample handling and data management that underpin reliable bioanalytical study outcomes.

Duties

• Prepare biological samples for method validation and assist with method development and troubleshooting.
• Weigh reference compounds and prepare stock and working solutions, standards, and QC samples.
• Aliquot control matrices and document all project work according to Q2 Solutions and GLP processes.
• Perform pipette maintenance and verification and other laboratory maintenance as required.
• Maintain housekeeping standards and assist in maintaining adequate supplies.
• Work with automated instrumentation and interface with Sample Management to request and return quality control samples.
• Use LIMS system to set up and edit worklists and manage bioanalytical data.
• Clean glassware, sustain six sigma in wet laboratory areas, and perform peer review of wet laboratory preparations.

Education & Experience

• Bachelor's degree in Biology, Chemistry, or related field, or equivalent combination of education, training, and experience in a GLP analytical laboratory.
• Familiarity with Good Laboratory Practices and a variety of pipettes; basic knowledge of math and chemistry.
• Basic mechanical skills and ability to work with potentially hazardous chemicals, infectious materials, and radioactive materials.
• Basic computer skills including word processing, spreadsheet, and network navigation; familiarity with LIMS systems.
• Ability to establish and maintain effective working relationships with coworkers, managers, and clients.

A key member of an analytical laboratory team, the Associate Scientist performs qualitative and quantitative analyses using established and experimental test methods, assists in study design, and supports method development and validation in a cGMP-regulated environment. Collaborating with analysts and departmental leadership, the Associate Scientist builds scientific capability that ensures regulatory compliance and meets individual and departmental performance goals.

Work Activities

• Perform analyses using various techniques including established and experimental test methods, standards, and guidance; use instrumentation both qualitatively and quantitatively.
• Assist in completing projects from protocol to final report with guidance; develop and validate methods with guidance.
• Train analysts as appropriate and keep current with new analytical technology.
• Assist in preparation of technical reports, work instructions, SOPs, and qualification documentation.
• Assist in lab study design, study plans, and protocols; perform lab investigations, OOS, and OOT as required.
• Apply required cGMP regulations and internal QA procedures and adhere to established laboratory safety procedures.
• Meet individual and departmental goals and work autonomously and as part of a team.

Position Requirements

• BS in Engineering, Chemistry, or related technical science.
• 0-3 years of experience in functional/physical testing and cGMP environments.
• Familiarity with all relevant SOPs as per company policy related to the position.
• Self-motivated with adaptability, a positive attitude, and willingness to learn and apply new analytical techniques.
• Ability to stand in a laboratory environment, operate tools and controls, lift up to 25 lbs, and travel up to 5% of the time.

The Associate Scientist builds and qualifies potency assays in support of process development, drug release, stability testing, and characterization at Aptevo, working alongside other scientists to maintain laboratory operations and evaluate data in compliance with Aptevo quality standards. Based within a cross-functional biologics research environment, the Associate Scientist enables product release and R&D advancement by developing cell-based assays, authoring qualification documentation, and performing routine cGMP-compliant testing.

Key Deliverables

• Perform mammalian tissue culture and reagent preparation for use in assay work.
• Develop potency assays to support R&D development and conduct potency assay qualification.
• Write related documents including test methods, protocols, and reports associated with qualification.
• Perform routine stability and release potency assays under R&D and cGMP compliance.
• Process data generated from assays in compliance with Aptevo standards and prepare high-level scientific data presentations and study reports.
• Ensure instruments and equipment are properly maintained for cGMP use, order and maintain laboratory supplies, and communicate across group functions.

Knowledge Skills & Abilities

• BS degree in a related field with 5 years of relevant experience, or MS degree with 3 years of relevant experience.
• Experience drafting and adhering to SOPs and in method qualification and utilization of DOE; familiarity with GxP and other regulatory requirements.
• Excellent tissue culture skills and experience developing cell-based assays with a focus on potency.
• Strong data analysis, interpretation, and organizational skills with keen attention to detail.
• Strong interpersonal communication skills and proven ability to communicate experimental procedures and results to peers and upper management.
• Ability to multitask across functional groups and projects and work independently as well as in a team environment.

As the Associate Scientist, this role executes trialling programs from stages 3 to 6 to characterize crop varieties across environments, contributing to all plot-level operations from seed preparation through harvest. The trialling and breeding team relies on this work to generate accurate phenotypic and environmental data stored in tools such as EZ Capture, Spirit, and MINT, enabling continuous improvement of phenotyping methods and breeding program outcomes.

Job Functions

• Perform trialling programs led by the trialling scientist (stages 3 to 6) to characterize varieties in their environments.
• Contribute to all plot-level operations from seed preparation through harvest and participate in the development of work instructions and proper follow-up of procedures.
• Monitor, score, and measure required phenotypic traits to ensure highest quality data and participate in the development of new phenotyping methods with higher quality and better throughput.
• Complete and store phenotypic and environmental data in appropriate tools such as EZ Capture, Spirit, and MINT.
• Contribute to KPI improvement, implementation, and key actions in the area of expertise and exchange best practices with counterparts within and across crops for continuous improvement.
• Interact under the trialling scientist's responsibility with PSL and breeders to exchange on objectives, actions, results, and improvement plans.
• Proactively follow HSE policies at all times.

Minimum Qualifications

• Technical knowledge in agronomy including crop knowledge, soil knowledge, farming practices, and machinery, as well as data collection, quality checking, and storage.
• Ability to work within a matrix environment spread across geographies and cultures.
• Agility and flexibility to support breeding, product selection, and business objectives.
• Strong organizational skills to complete large field programs with timely and complete reporting of information.
• Effective communication and planning skills.

The Associate Scientist produces results in a novel microfluidic experimental platform designed to screen NANOBODY Molecule lead drug candidates for therapeutic applications, maintaining and troubleshooting the optical and fluidic systems on which assay quality depends. Working closely with project-oriented teams, the Associate Scientist advances drug candidate selection by executing cell-based and biochemical assays and communicating findings that guide therapeutic development decisions.

Operational Focus

• Maintain and troubleshoot microfluidic and optical setups.
• Perform cell-based assays including ligand binding and cell signalling.
• Use mammalian cell culture technologies including cell line generation, maintenance, and quality control.
• Perform flow cytometry experiments and biochemical assays.
• Analyze data and prepare written reports of results.
• Communicate results and observations to the team and contribute actively to project-oriented teams.

Requirements

• Bachelor's or Master's degree in Bioengineering or equivalent.
• Experience in the above-mentioned responsibilities would be an asset.
• Experience in building and maintenance of microscopes and microfluidics.
• Proficient in MS Office suite including Word and PowerPoint; LabView experience is an asset; advanced Excel is a plus.
• Solid analytical and problem-solving skills alongside perseverance and a hands-on mentality.
• Proactive approach with high sense for quality, accuracy, and detail.
• Team-oriented attitude with flexibility, enthusiasm, and ability to work independently.
• Fluency in English.

Reporting within the Process Development Analytical Services team of the AD Department, the Associate Scientist supports analytical transfer activities and assay implementation for routine testing by coordinating non-GMP samples and executing cell culture, flow cytometry, and multi-method analytical workflows. Partnering with local AD scientists, analysts, and the broader Janssen organization, the Associate Scientist advances smooth method transfer and timely delivery of analytical test results that sustain product development timelines.

Key Responsibilities

• Work with viruses, cells, proteins, and nucleic acids from sample preparation through analysis and data treatment.
• Accept and coordinate all non-GMP samples and plan, coordinate, and execute analytical assays with a focus on method transfer and routine testing.
• Perform cell culture and viral work (BSL2), flow cytometry, and additional methods such as qPCR, ELISA, Octet, HPLC, cGE, and SoloVPE as needed.
• Serve as specialist of the electronic analysis order system of PDAS (eGondola) and collaborate closely with local AD scientists, analysts, and broader Janssen colleagues.
• Summarize and present experimental data to the team.
• Create and review GLP documentation including study plans, assay protocols, work instructions, and equipment instructions in close consultation with AD scientists.
• Support routine laboratory activities including equipment maintenance, material ordering, and stock management.
• Follow project plans including protocols, SOPs, and work schedules in a self-sufficient manner.

Qualifications & Experience

• MSc degree in a life science discipline with work or research experience in a relevant field.
• Experience with cell culture/viral work and flow cytometry is a major advantage.
• Good organizational and planning skills; independent working style with ownership of assigned tasks to plan and deliver according to project timelines.
• Team player with a communicative personality able to integrate into a multicultural environment and collaborate efficiently.
• Very good communication in English; German is an advantage.

The Associate Scientist advances drug candidate evaluation in Sanofi's Immuno-Oncology portfolio by designing and executing cellular and molecular biology in vitro studies and developing immune cell assays for target validation and mechanistic understanding. The multidisciplinary research environment relies on the Associate Scientist's expertise in primary cell culture, multi-color flow cytometry, and nanoparticle drug delivery to translate scientific insights into actionable outcomes for oncology programs.

Core Responsibilities

• Contribute to research efforts in Sanofi Oncology to progress new immune-therapeutic approaches in cancer.
• Develop and implement new in vitro immune cell assays for target validation, drug activity evaluation, and mechanistic understanding of new therapeutic approaches.
• Conduct molecular biology assays in the context of developing new nanoparticle drug delivery systems.
• Maintain working knowledge of current experimental techniques and literature in cancer immunology.
• Analyze, interpret, and present experimental results at project team meetings and to multi-disciplinary research groups.
• Communicate with managers and collaborators in an open and effective manner.
• Provide and promote support for operational procedures according to Sanofi values, ethics, and security.
• Work autonomously and proactively for the rigorous execution of experiments in alignment with laboratory processes.

Skills & Qualifications

• Master's or engineering degree with extensive experience in immuno-oncology, particularly in the field of myeloid cells.
• Extensive experience in molecular biology, primary cell culture, and immune cell assay techniques including multi-color flow cytometry.
• Experience in nanoparticle drug delivery systems is a plus.
• Strong analytical, organizational, and communication skills.
• Proactive and independent in daily laboratory research activities with excellent teamwork skills and flexibility.
• Fluent in English speaking, reading, and writing.

Associate Scientist II joins the Foil and Fiber Product support team to perform laboratory tasks and data analysis that sustain the manufacturing of blood gas and blood chemistry analyzers and their consumables. The work directly supports the production department and existing product support teams by validating new components, troubleshooting discrepancies, and ensuring documentation and ISO Quality Management System compliance throughout the product lifecycle.

Performance Expectations

• Perform a variety of scientific activities to support the development, maintenance, improvement, and understanding of products and reagent production processes.
• Prepare materials, perform experiments, gather data, carry out analysis, and reach conclusions; may also design experiments.
• Document experiments and other lab or production activities, prepare reports and summaries, and present results and conclusions.
• Validate new product components, processes, and equipment.
• Collaborate and communicate with colleagues in related areas to provide work support, exchange information, and ensure efficient processes.
• Ensure documents are completed according to SOPs and reflect current manufacturing processes.
• Operate within an ISO 9001:2008/14001:2004 Quality Management System.
• Perform troubleshooting activities and corrective actions on discrepancies, product failures, or other problems.

Required Qualifications

• Bachelor's degree in biology, chemistry, or other scientific field, or equivalent education with 2+ years of work experience.
• Analytical and problem-solving skills.
• Strong verbal and written communication skills.
• Organizational skills and ability to plan work independently and cross-functionally.
• Takes initiative and is accountable with a detail-oriented focus.
• Ability to work well under pressure and handle the stress of deadlines.

Embedded within the Core Consumables Development team in Singapore, the Associate Scientist 1 develops and characterizes high-quality consumable reagents for Illumina sequencing platforms through biophysical and biochemical experimentation and cross-functional collaboration with protein research, manufacturing, and QA/QC teams. Working closely with platform integration and operations colleagues, the Associate Scientist 1 refines reagent stability and performance parameters that enhance robustness across Illumina's entire reagent platform and directly support NGS product quality.

Accountabilities

• Engage in cross-functional collaboration with protein research teams, platform integration teams, Reagent Manufacturing, Operations, and QA/QC to accelerate development of novel consumable reagents.
• Develop methods, techniques, and evaluation criteria for obtaining world-class results as part of a team.
• Execute biophysical and biochemical characterization experiments for critical components of Illumina sequencing reagents under supervision.
• Employ analytical tools for protein or small molecule characterization and demonstrate their predictive value for reagent performance and quality.
• Employ and explain statistical methods to drive decisions.
• Write technical reports and communicate effectively to local leadership.
• Be a strong team member within multi-disciplinary teams.

Technical Qualifications

• B.Sc./B.Eng. or M.Sc./M.Eng. in biochemistry, biochemical/chemical engineering, biomaterial, or equivalent.
• 4+ years of work experience in biochemical, pharma, chemical, or equivalent industries.
• Familiarity with quantification and qualification techniques such as DSC, DLS, CD, optical microscopy, rheometry, electrophoresis, liquid chromatography, and activity assays.
• Experience with enzymes involved in NGS sample preparation or methylation assays such as transposases, ligases, TET, or APOBEC is a plus.
• Experience operating pilot-scale or large lab-scale cell culture processes at 20 litres or above is an advantage.
• Understanding of protein biochemistry, engineering, and structure is a plus; NGS experience is a plus.
• Can-do attitude with ability to work collaboratively in a team and good communication skills.

Embedded within a matrixed pharmacology research team, the Associate Scientist I performs in vivo experiments to interrogate PK/PD relationships and target management, contributing to the troubleshooting and optimization of in vivo models. Working closely with project team members and group leads, the Associate Scientist I advances pharmacology study outcomes by executing tissue collection, immunohistochemistry, and microscopy analyses that translate into actionable experimental reports and presentations.

Areas of Ownership

• Work within a matrixed environment to support progress towards project and team goals.
• Help troubleshoot, optimize, and develop in vivo models.
• Perform in vivo experiments to interrogate PK/PD relationships and target management.
• Prepare experimental reports including detailed methods and materials, raw data, data analyses, graphs, and conclusions.
• Record experimental methods and results in the electronic laboratory notebook.
• Present experimental results during group and project team meetings.
• Follow laboratory safety and data integrity guidelines.

Education & Experience

• Master's Degree in Pharmacology, Neuroscience, or Biology with 1–3 years of experience, or Bachelor's Degree with 2–4 years of experience.
• prior research laboratory experience required with industry experience preferred.
• Prior experience with independent handling and dosing of laboratory animals via oral, intraperitoneal, and subcutaneous routes for pharmacology studies.
• Familiarity with small animal surgery, in vivo perfusion, tissue collection, cryostat sectioning, and immunohistochemistry.
• Familiarity with microscopy analysis including confocal and/or 2-photon and image quantification.
• Fundamental knowledge of pharmacology including agonist/antagonist/modulator concepts and PK/PD relationships.
• Experience in multicolor flow cytometry is a plus.

As the Associate Scientist, this role develops and validates analytical methods for vitamins, carotenoids, and lipids across feed and food matrices while supporting continuous improvement of HPLC, LC-MS, and GC-based workflows within the R&D Analytics Product Application team. The team relies on this work to evaluate and implement new analytical technologies and deliver timely quantitative results that advance innovation projects across multiple nutrition and health ingredient applications.

Key Deliverables

• Develop and validate analytical methods for quantification of vitamins, carotenoids, lipids, impurities, and degradation products in feed and food applications.
• Execute quantitative analysis of carotenoids, vitamins, and new health ingredients in various matrices based on existing methods and support continuous method improvement.
• Evaluate and implement new analytical technologies; take initiative to speed up, miniaturize, and automate sample preparation and analytical workflows.
• Calibrate and maintain analytical laboratory equipment.
• Deliver oral and written reports of performed work and results in a cross-functional, highly dynamic innovation environment.

Qualifications & Experience

• Bachelor's degree with at least 5 years of experience, or Master's degree with experience in analytical chemistry or related fields.
• Sound expertise in HPLC, LC-MS, and GC technology; knowledge of CE and SFC is a plus.
• Knowledge of feed/food sample workup and quantification of small molecules such as vitamins, carotenoids, or natural products is an advantage.
• Experience with computerized lab environments including LIMS, CDS, electronic lab notebooks, and scientific databases.
• Knowledge of digital transformation and data management is a plus.
• Open-minded team player with flexibility to work in different innovation projects or laboratory teams and good presentation skills.
• Good command of English is required; German is a plus.

The Associate Scientist, Cell & Gene Therapy develops analytical methods and establishes internal laboratories to support analytical testing for T-cell therapy products, contributing to risk assessments and method lifecycle activities across cell and gene therapy programmes. Based within a matrix team environment and collaborating with internal and external partners, the Associate Scientist, Cell & Gene Therapy strengthens analytical capability and product control strategies that enable the advancement of cell and gene therapy pipelines toward clinical readiness.

Delivery Expectations

• Develop analytical methods and support establishing internal laboratories for analytical testing of T-cell therapy products.
• Support external collaborations to enhance analytical capabilities and enable a robust and rapid testing strategy for cell and gene therapy products.
• Participate in risk assessments to develop robust product control strategies for cell and gene therapy programmes.
• Maintain laboratory equipment and critical reagents including analytical method control preparation.
• Assist in the analytical method lifecycle during product development including risk assessments and preparation of qualification reports.
• Support capability build in other functional areas as needed.

Qualifications & Experience

• BSc degree in a relevant life science discipline; MSc degree preferred with experience in cell biology, immunology, or related discipline.
• Industrial experience in cell culture with a minimum of 2 years.
• Experience in developing cell-based methods for producing and analyzing primary mammalian cell lines and T-cells, and characterizing these cells by flow cytometry.
• Experience working with and maintaining relationships with internal or external collaborators and in preparing oral and technical reports to influence strategic decisions.
• Strong organisational and excellent interpersonal communication skills.
• Ability to work independently and proactively within a matrix team environment with familiarity with basic statistics.

Associate Scientist designs and implements in vitro immunological assays to support an innovative immuno-oncology drug discovery program within the Immunomodulation of tumor cell sensing cluster. The work directly supports the Line Manager and Project Leaders by delivering primary cell-based assay data on drug candidates and targets of interest, with the Associate Scientist enabling program advancement through expertise in human primary immune cells, flow cytometry, and genome engineering techniques.

Scope of Work

• Work with the Line Manager and Project Leaders to design, develop, and run in vitro primary cell-based assays supporting drug candidate development and targets of interest in immuno-oncology.
• Work with Project Leaders to ensure timely delivery of data and report any issues.
• Provide clear reports of analyzed data and presentations to group and project meetings.
• Communicate ideas and findings to the team and maintain laboratory notebooks to required standards.
• Adhere to HSE requirements and ethics rules according to Sanofi values.

Experience & Qualifications

• BSc/MSc or equivalent with significant practical experience in an academic or biotech/industrial setting.
• Experience working with primary human immune cells and in isolation and culture of human primary cells and cell-based functional assays such as tumor killing assays.
• Expertise in tumor cell sensing and innate immune activation or a related field.
• Experience in multi-color flow cytometry and/or imaging technologies such as Incucyte is desirable.
• Basic knowledge of genome engineering techniques including CRISPR/Cas, siRNA, and Lentivirus would be appreciated.
• Science-driven and proactive with ability to work independently and with a degree of autonomy; flexible and strong team player attitude.